Seconding this! Make sure you get the "special tour". It was an absolute highlight of my trip.
If you are interested in power infrasture it's a must see. If you're afraid of heights, perhaps not so much.
There is one part where you are invited to walk on a catwalk that's very high up (an outdoor staircase sort of like a fire escape). My recollection is that walking on it is not mandatory for the tour, but I'm not absolutely certain of that.
You're also invited, but not required, to look over the edge of the dam from the top, which is also very far down.
JetBlue is a small rival (JetBlue at ~5% of US traffic, Spirit at ~3%) to the big 4 United/American/Southwest/Delta (each with ~17%). At least on the surface, a larger JetBlue might be more competitive rather than forcing them into the unequal partnerships like they have with United at the moment.
Certainly, some jobs would be lost, but I do think that Spirit dying is a worse outcome than joining another small airline.
This is actually what is thought to partially have caused the damage seen previously. The new trajectory is supposed to just have a single heating pulse instead of two.
Well, the IRGC folks actually fighting probably don't have a luxurious future in a reformed Iran, so they might not be far off fighting for their lives.
Except this is not how medical regulation has worked in the US. This particularly is a new and stricter standard required for this particular vaccine. Even the new Trump policies for COVID vaccines now specifically requires a placebo -- comparison against standard-of-care would not be accepted.
Huh? The FDA's main guidance document on this topic, issued in 2007 with no major overhaul since [0], states that comparative efficacy or effectiveness data is valuable when:
- The comparator vaccine is indicated for the same population.
- The comparator has existing clinical effectiveness data.
In other words, the trial design should use a benchmark that makes sense given what doctors and guidelines actually recommend today. For older adults, evidence over the past 15+ years has shown that enhanced flu vaccines often provide better protection than standard-dose ones. The study used standard-dose vaccines as far as we can see.
The only oddity here is that the FDA apparently approved the study previously
The document describes proof of effectiveness as supported by demonstrating "non inferiority to... a US licensed product". So yes, a (licensed) benchmark, but I see no references to a requirement for only testing against the best standard of care. It's a separate question about whether it should be though, and the cfr is quite vague throughout, so I would probably expect this isn't an illegal move (assuming arbitrary and capricious isn't held by a court), but I don't see it supported by precedent.
You say economics instead of emotion, but your last sentence is emotion.
If capex is your concern, explain the purpose of canceling an almost-complete farm.
If energy breakevens are your concern, explain how this breakevens compares against, e.g. oil liquids.
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